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Departmental Structure and Leadership
Cell and Tissue Biology
Oral and Maxillofacial Surgery
Orofacial Sciences
Preventive and Restorative Dental Sciences

Diane Barber, PhD, Interim Chair

  • Program in Craniofacial and Mesenchymal Biology
    Ophir Klein, MD, PhD, Director

M. Anthony Pogrel, DDS, MD, FACS, FRCS, Chair

  • Center for Orofacial Pain
    Charles McNeill, DDS, Clinic Director

Deborah Greenspan, BDS, DSc, Chair

  • Division of Craniofacial Anomalies
    Karin Vargervik, DDS, Division Chair
  • Division of Oral Medicine, Oral Pathology and Oral Radiology
    Richard Jordan, DDS, MS, PhD, Division Chair
  • Division of Orthodontics
    Karin Vargervik, DDS, Interim Division Chair
  • Division of Pediatric Dentistry
    Pamela Den Besten, DDS, MS, Division Chair
  • Division of Periodontology
    Mark Ryder, DMD, Division Chair

William F. Bird, DDS, DrPH, Interim Chair

  • Division of Behavioral Sciences, Professionalism and Ethics
    Linda Centore, PhD, Division Chair
  • Division of Biomaterials and Bioengineering
    Grayson Marshall, PhD, DDS, MPH, Division Chair
  • Division of General Dentistry
    Sheila Brear, BDS, Division Chair
  • Division of Endodontics
    Frederick Finzen, DDS, Interim Division Chair
  • Division of Oral Epidemiology and Dental Public Health
    Jane Weintraub, DDS, MPH, Division Chair
  • Division of Prosthodontics
    Frederick Finzen, DDS, Division Chair
  • Program in Biomaterials, Biophysical Sciences and Engineering
    John Featherstone, PhD, Program Director
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The Department of Cell and Tissue Biology (CTB) at the UCSF School of Dentistry has active research programs in cell and developmental biology, tissue remodeling and repair, genesis and progression of head and neck cancers, and molecular pathogenesis. Investigators in this Department have developed several National Institutes of Health-supported centers and programs over the past decade. These include the Comprehensive Oral Health Research Center, which focuses on strategies for promoting tissue repair, the UCSF Oral Cancer Research Center, which is concerned with the genesis and progression of oral cancer, and, most recently, a project to catalogue the salivary proteome.

The Department of Cell and Tissue Biology is the administrative home for the new UCSF campus-wide Program in Craniofacial and Mesenchymal Biology (CMB). This Program focuses on basic and translational research related to cellular and morphogenetic processes underlying development. These include cell migration and proliferation, signaling mechanisms underlying formation of mesenchymal tissues, the role of epithelial-mesenchymal interactions in tissue formation, and the properties and differentiation potential of mesenchymal stem cells. These areas of focus provide strong opportunities for interaction with the UCSF Campus-wide Developmental & Stem Cell Biology Program, with research campus-wide in tissue engineering and biomaterials, and with the Craniofacial Anomalies Center in the School of Dentistry.

The Department is also one of the founders of the new UCSF campus-wide Program in Microbial Pathogenesis. Research within the department related to this area currently focuses on bacterial adherence mechanisms, oral candidiasis, and viral infections in the placenta and immune protection. The Department of Cell and Tissue Biology is collaborating with the departments of Preventive and Restorative Dental Sciences and of Orofacial Sciences in the School of Dentistry and the Microbial Pathogenesis Program to recruit in the important area of biofilms research.

The Department of Cell and Tissue Biology houses the UCSF Mouse Microarray Consortium. It is also affiliated with the newly established Mass Spectrometry Facility, within UCSF’s Biomolecular Resource Center.

Faculty in Department of Cell and Tissue Biology teach in the Biomedical Sciences course sequence in the DDS pre-Doctoral program, with a focus on human anatomy and embryology, head and neck anatomy, histology and neuroscience. Cell and Tissue Biology faculty members also teach in a number of courses given by graduate programs, including the Biomedical Sciences Graduate Program and Oral and Craniofacial Sciences Graduate Program.

The Department of Cell and Tissue Biology is actively recruiting new faculty in the area of Developmental and Molecular Biology related to the CMB Program and in the Microbial Pathogenesis Program.

Interim Chair: Dr. Diane Barber
University of California, San Francisco School of Dentistry
513 Parnassus Ave - S-612
Campus Box 0512
San Francisco, CA. 94143 - 0512

For additional information please visit the Cell and Tissue Biology website.
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The Department of Oral Maxillofacial Surgery (OMFS) teaches both theoretical and clinical courses in the predoctoral dental curriculum and offers instruction in medical emergencies in the dental hygiene and predoctoral dental programs.

Basic research in the department include investigations of the mechanisms of bone growth and replacement, the use of lasers and mechanisms of pain, and studies of treatment and outcomes of implant, orthognathic, TMJ, and reconstructive surgery.

The department provides clinical care in oral and maxillofacial surgery to ambulatory patients at the Dental Clinics Building, the postgraduate OMFS Clinic at Moffitt Hospital, and the oral and maxillofacial surgery clinic at San Francisco General Hospital. Treatment for hospitalized patients is provided at Moffitt/Long Hospital, San Francisco General Hospital, UCSF/Mount Zion, and Veterans Affairs Medical Center.

The department also provides elective courses in oral and maxillofacial surgery at San Francisco General Hospital and implant clerkships where students learn to assist with surgical procedures. Other externships allow dental students to spend from two to six weeks at other dental schools around the country.
The department’s postgraduate residency program leads to certification in OMFS with an MD degree. A PhD is also offered to suitable applicants. Please write to the program director for specific information on postgraduate programs in oral and maxillofacial surgery

Chair: Dr. M. Anthony Pogrel
521 Parnassus Avenue, C 522
San Francisco, CA 94143-0440

For additional information please visit the Oral and Maxillofacial Surgery website.

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The Department of Orofacial Sciences is a new and exciting academic and clinical enterprise, the role of which is teaching and practicing the diagnosis and treatment of localized and systemic oral diseases and developmental conditions, and advancing knowledge about them. Several clinical disciplines comprise this Department including Craniofacial Anomalies, Oral Medicine, Oral Pathology, Oral Radiology, Orthodontics, Pediatric Dentistry and Periodontology. Cross-disciplinary clinical, teaching and research activities characterize this Department, which benefits from strong interactions within the Dental School, other campus Schools and the Medical Center. Educational activities are broad, providing both predoctoral and postdoctoral students alike with a strong basis of knowledge and clinical experience.

Research in the Department covers a broad spectrum of basic, translational and clinical sciences that complement the clinical activities of the Department. These include extramurally funded studies of oral mucosal and salivary gland diseases, including those common in people with HIV infection (conducted through the Oral AIDS Center), oral cancer, xerostomia, Sjögren’s Syndrome (the Sjögren’s International Collaborative Clinical Alliance), and new methods for diagnosing and treating periodontal diseases. In addition, clinical research studies assess the effect of orthodontic treatment on the form and function of the craniofacial complex, new approaches to imaging, the interrelationships of the neuromuscular systems on muscle function and bone growth, and seek to understand the variations in outcome of interdisciplinary treatment of patients with craniofacial anomalies. Studies of enamel and dentin formation are key to new initiatives for tissue engineering of tooth structures, as well as for understanding dental pathologies such as fluorosis and amelogenesis imperfecta.

Patient treatment services provide the highest level of patient care focusing on the latest and most effective treatment methods. The Oral Medicine Clinical Center (formerly known as the Stomatology Clinical Center) specializes in the diagnosis and treatment of oral soft tissue and salivary gland diseases and serves as the basis for predoctoral student education. The Oral Pathology Diagnostic Laboratory, one of the largest in Northern California, offers world-class tissue diagnostic services for dental and medical practitioners. Orthodontics provides state-of-the-art care for children and adults with dental malocclusions. Pediatric Dentistry provides primary and tertiary care for dental diseases and prevention for infants and children. Periodontology focuses on the diagnosis and management of the various periodontal conditions and provides treatment with osseo-integrated implants. The Center for Craniofacial Anomalies provides multidisciplinary consultation and comprehensive treatment of children with various birth defects.

Postgraduate programs in Orthodontics, Pediatric Dentistry, Periodontology and Oral Medicine complete the department’s instructional activities. Most students in these training programs are concurrently enrolled in an MS degree program in Oral and Craniofacial Sciences. Additional training leading to the PhD in Oral and Craniofacial Sciences is also available.

Chair: Dr. Deborah Greenspan
University of California, San Francisco School of Dentistry

513 Parnassus Ave
Campus Box 0422
San Francisco, CA. 94143 - 0422


Craniofacial Anomalies
Oral Medicine, Oral Pathology and Oral Radiology
Pediatric Dentistry

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The Department of Preventive and Restorative Dental Sciences conducts multidisciplinary instruction, research, and patient care programs through its seven divisions: behavioral sciences, professionalism and ethics, biomaterials science and bioengineering, general dentistry, endodontics, oral epidemiology and dental public health, and prosthodontics. Preclinical and clinical educational programs operate within the laboratories and clinics of the dental facilities on campus and through the school's satellite facilities, including the community clinics at San Francisco General Hospital and Buchanan Street. The postprofessional specialty clinic in graduate prosthodontics is located on campus.

In the predoctoral dental curriculum, the divisions of behavioral science, professionalism and ethics and oral epidemiology & dental public health teach a stream of courses called "Successful Dental Practice" spread throughout the four-year curriculum. This core curriculum includes clinical care and current issues in dentistry, behavioral sciences, ethics, quality assurance, and practice management.

The educational goals of the Successful Dental Practice program include developing 1) behavioral management and communications skills, 2) ethical dentist-patient relations, 3) sensitivity and social skills, 4) practice management skills, and 5) the ability to cultivate self-reflections and well-being. The program integrates several disciplines including basic, clinical, and behavioral sciences under a common mission to introduce a more participatory educational format.

Research in the department spans the spectrum from basic to translational to clinical research. Areas of emphasis include the application of the analytical techniques of materials science to the characterization of dental hard tissues and restorative materials; characterization and testing of dental materials; the effects of restorative procedures on the dental pulp; basic research into that organ's biology; psychological aspects of temporomandibular joint disorders; preventive, diagnostic, and therapeutic laser applications in dentistry; caries risk assessment; and caries prevention and management.

Research in oral epidemiology, public health, and behavioral science includes a spectrum of ongoing projects on the epidemiology of oral diseases and the delivery of dental care. Faculty in the department have ongoing studies in patient and population-based research, including clinical trials and other types of clinical research. One epidemiologic study is examining how dental diseases run in families. A series of studies in the behavioral sciences is investigating the effect of dentists' attitudes toward domestic violence and health care professionals' barriers to providing preventive care in a managed care environment. Ongoing studies also include the research into the use of smokeless tobacco products by professional baseball players, and developing the development of community-based tobacco prevention and cessation interventions. Faculty are working with dental insurers to develop new, nonsurgical approaches and insurance products that will emphasize preventive measures to prevent, treat, and manage dental caries that will emphasize preventive measures and nonsurgical procedures.

The department offers a three-year residency program in prosthodontics. In addition, the department offers postgraduate education in dental public health and epidemiology, in conjunction with the School of Public Health at UC Berkeley as part of the Dentist Scientist Award Program for dentists interested in combining specialty training with a PhD in epidemiology. An accredited dental residency program in dental public health is also available for dentists who are interested in specializing in dental public heath.

Links to information on the following:
Preventive and Restorative Dental Sciences
Dental Scientist Training Program
Dentist-Scientist Award Program

Interim Chair: Dr. William F. Bird
Vice-Chair, Research: Dr. Grayson Marshall
Vice-Chair, Leadership Development: Dr. Robert Ho
Vice-Chair at Large: Dr. Frederick Finzen

707 Parnassus Avenue
San Francisco, CA 94143-0758


Behavioral Sciences, Professionalism and Ethics
Biomaterials Science and Bioengineering
General Dentistry
Oral Epidemiology and Dental Public Health

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Last updated: July 28, 2010